It has potential anti-angiogenic, anti-glycating, anti-hyperglycaemic,antimicrobial, fungitoxicity, neuroprotective, antimitogenic, chemo-sensitizing, anti-obesity, anti-inflammatory, anti-steatotic, and memory-enhancing properties. Fraction sorbed to airborne particulates (phi): 0.0379 (Junge,Mackay) Note: the sorbed fraction may be resistant to atmospheric oxidation Soil Adsorption Coefficient (PCKOCWIN v1.66): Koc : 12.39 Log Koc: 1.093 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]: Rate constants can NOT be estimated for this structure! Syringic acid, also known as syringate or cedar acid, belongs to the class of organic compounds known as gallic acid and derivatives. Description: Syringic acid is a potential antioxidant used in traditional Chinese medicine and is an emerging nutraceutical. PubChem is the world's largest collection of freely accessible chemical information. Gallic acid and derivatives are compounds containing a 3,4,5-trihydroxybenzoic acid moiety. Syringic acid may protect RGC-5 cells against apoptosis induced by H2O2 through the activation of PI3K/Akt signaling pathway. Syringic acid is an extremely weak basic (essentially neutral) compound (based on its pKa). solubility in organic solvents is a key factor for phenol recovery, studies referring to corresponding prediction data are rather limited. A recent study reported the prediction of gallic acid solubility in methanol, ethanol, water, and ethyl acetate at a temperature range of 298.2 to 333.2 K with the modified Apelblat model. Syringic acid shows a time- and dose-dependent (IC50 = 0.95-1.2 mg/mL) antimitogenic effect against cancer cells with little cytotoxicity on normal fibroblasts (≤20%). Sign Up for Email Customer Service +1 800-234-7437 help@thermofisher.com Find chemical and physical properties, biological activities, safety and toxicity information, patents, literature citations and more. SA is a natural and notable antioxidant activity compound with its limited bioavailability ascribable to its poor aqueous solubility and fast elimination. The PSM used in the study was syringic acid, C 9 H 10 O 5 (≥95.0% purity, molecular weight 198.17 g/mol, 5.78 mg/mL water solubility at 25 °C, pKa value … In this study, syringic acid-loaded TPGS liposome (SA-TPGS-Ls) was successfully prepared to improve oral bioavailability of syringic acid (SA). Recently, TPGS has become a perfect molecular biomaterial in developing several carrier … Search chemicals by name, molecular formula, structure, and other identifiers.