Epichlorohydrin, benzyltriethylammonium chloride and 4,4′-methylenedianiline (DDM), Sodium hydroxide were purchased from Adamas Company, China. Protocatechuic acid was provided by Tianjin institute of industrial biotechnology, Chinese Academy of Sciences. Flavonoids and polyphenols are heterocyclic molecules that have been associated with beneficial effects on human health, such as reducing the risk of various diseases like cancer, diabetes, and cardiovascular and brain diseases.
For each heterologous reaction step, we analyzed several potential candidates for their expression and activity in yeast to compose a functional cis,cis-muconic acid synthesis pathway. Sigma-Aldrich offers a number of Protocatechuic acid products.

Recent studies indicate that it could be used as a protective agent against cardiovascular diseases and neoplasms.

Protocatechuic acid (PCA) is a type of widely distributed naturally occurring phenolic acid. View information & documentation regarding Protocatechuic acid, including CAS, MSDS & more. Chemical Synthesis (5) Flavors and Fragrances (1) Special Grade. Protocatechuic acid (3, 4-dihydroxybenzoic acid) is a natural phenolic compound found in many edible and medicinal plants.
The pathway consists of three heterologous microbial enzymes, 3-dehydroshikimate dehydratase, protocatechuic acid decarboxylase composed of three different subunits, and catechol 1,2-dioxygenase. Synthesis, structure, urease inhibitory, and cytotoxic activities of two complexes with protocatechuic acid derivative and phenanthroline. Analytical (2) analytical standard (1) certified reference material (1) Food Grade (1) Halal (1) Kosher (1) Purum (1) ... Protocatechuic acid ethyl ester. 2.2. It is a conjugate acid of a 3,4-dihydroxybenzoate. All solvents were utilized as received. (2015).

It derives from a benzoic acid. Protocatechuic acid (PCA), as 3, 4-dihydroxybenzoic acid, is a water-soluble monomeric phenolic acid and widely distributed in many traditional Chinese herbal medicines.